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Percentages of the ~180-kDa corin fragment or all there soluble corin fragments were estimated.D. From four independent experiments. Plasma levels of soluble corin in people with WT and the variant alleles. Plasma degrees of NT-pro-ANP in individuals with WT and the variant alleles.Total size imagePlasma Soluble Corin and NT-pro-ANP LevelsWe also measured plasma corin in individuals with WT and the insA variant CORIN alleles. The known levels in 215 normal people with the WT allele were 0. 6D). However, the sample size in the normotensive group was as well small for statistical analysis. In a subset of samples from individuals with the WT allele, plasma corin amounts were reduced hypertensive individuals .