December 17, 2017 The findings, published today in the web journal PloS One, open new possibilities for gaining a larger understanding of Alzheimer’s disease and other neurological diseases and for developing therapies to halt its progression, according to senior writer Karen E. Duff, PhD, professor of pathology at CUMC and at the brand new York Condition Psychiatric Institute. Alzheimer’s disease, the most typical form of dementia, is seen as a the accumulation of plaques and fibrous tangles in human brain cells known as neurons. Postmortem studies of human brains and neuroimaging research have recommended that the disease, especially the neurofibrillary tangle pathology, starts in the entorhinal cortex, which plays a key role in memory.Dr. Jeffrey Borenstein is normally president of the mind & Behavior Research Foundation in NEW YORK, which supports research into ailments such as schizophrenia. Borenstein believes that a multipronged approach can curb the use of hospital ERs while a last-resort ‘back-up’ for those who have the illness. First, ‘we have to improve our [health care] system so that people who have schizophrenia have appropriate access to outpatient care on an ongoing basis,’ he said. ‘We also need to improve the option of casing, including supportive housing, to lessen the true quantity of homeless people who have schizophrenia who end up in the ER,’ he added. ‘Finally,’ Borenstein said, ‘we need to continue working to develop new and improved types of treatment, including medications and various other therapy to help people with schizophrenia business lead productive lives.’ Birnbaum agreed.