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A systematic overview of the literature was performed in the electronic database of Medline and the Clinical Trials Registry Databases to study the result of aprotinin used in OLT on the intraoperative dependence on blood items and on the incidence of laparotomy for bleeding, thrombotic events and mortality. Using meta-evaluation as the statistical technique, this analysis was performed by doctors from the Section of Anesthesiology, First Affiliated Hospital, Nanjing Medical University. More clinic researches are had a need to confirm the full total result..