16 in the CDC’s Morbidity and Mortality Weekly Report . In another survey in the same problem of the MMWR, researchers led by S. Rene Lavinghouze discovered that, across the USA, more people want to break the smoking habit. The number of smokers who tried to quit in the past year more than doubled in 29 states and the U.S. Virgin Islands. From 2011 to 2013, the proportion of smokers who tried to give up increased in Hawaii and Puerto Rico, but decreased in New Mexico. In 2013, the number of smokers who attempted to avoid ranged from 56 % in Kentucky to 76 % in Puerto Rico and Guam, the statement showed. The researchers urge continued usage of anti-smoking programs to reach the Healthy People 2020 target of 80 % or more of smokers who made an attempt to quit previously year.The observed reductions in incidence and mortality act like the results of the United Kingdom11 and Italian12 studies of flexible sigmoidoscopy. Although the final end results of these trials are similar, there are notable differences among the research in enrollment criteria, compliance, screening frequency, and the use of endoscopic screening beyond your protocol. In the United Kingdom study, a single flexible sigmoidoscopic screening for individuals 55 to 64 years was performed. In the PLCO trial, two screenings were offered, and participants ranged from 55 to 74 years. In the United Kingdom study, 71.2 percent of individuals underwent a screening exam, whereas in the PLCO trial, 86.6 percent underwent at least one screening. In the PLCO trial, the next screening elevated the cumulative diagnostic yield of tumor or advanced adenoma by 26 percent among females and 34 percent among males.14 However, we cannot measure the incremental benefit of the second examination in colorectal-cancer mortality or incidence.